Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | IL1RN | P18510 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28919023 | 0.90 | CNR1 (0.45) | MEN1KMT2ACNR1TDP1AKR1C3 | |
| SCHEMBL28919080 | 0.88 | PKM (0.48) | MEN1KMT2AKCNH2HTR2AHTR2C | |
| SCHEMBL28919081 | 0.82 | KMT2A (0.54) | MEN1KMT2ACNR1METKCNH2 | |
| SCHEMBL30080374 | 0.79 | NR1H4 (0.54) | CNR1TDP1AKR1C3AKR1C2POLB | |
| SCHEMBL28919042 | 0.79 | NR1H4 (0.54) | CNR1TDP1AKR1C3AKR1C2POLB | |
| SCHEMBL28919079 | 0.76 | CNR1 (0.51) | MEN1KMT2ACNR1KCNH2POLB | |
| SCHEMBL7441288 | 0.74 | ALDH1A1 (0.49) | KMT2APOLBMAPT | |
| SCHEMBL28919025 | 0.73 | NR1H4 (0.58) | MEN1KMT2ACNR1TDP1AKR1C3 | |
| SCHEMBL30080500 | 0.73 | NR1H4 (0.58) | MEN1KMT2ACNR1TDP1AKR1C3 | |
| SCHEMBL28919039 | 0.70 | CNR1 (0.53) | MEN1KMT2ACNR1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521272-B | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2023-07-21 | — | — | CN | disclosed |
| CN-115521272-A | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2022-12-27 | — | — | CN | disclosed |