Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | COMT | P21964 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28612089 | 0.98 | ATM (0.39) | ATMKDM4EGAAALDH1A1MEN1 | |
| SCHEMBL23047247 | 0.79 | ATM (0.36) | ATMKDM4EGAAALDH1A1MEN1 | |
| SCHEMBL27928302 | 0.79 | FGFR1 (0.44) | KDM4EALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL20994199 | 0.75 | KDM4E (0.43) | ATMKDM4EGAAALDH1A1MEN1 | |
| SCHEMBL17875026 | 0.74 | ATM (0.48) | ATMKDM4EGAAALDH1A1MEN1 | |
| SCHEMBL20994183 | 0.73 | ATM (0.40) | ATMKDM4EGAAALDH1A1MEN1 | |
| SCHEMBL27916646 | 0.73 | ATM (0.40) | ATMKDM4EGAAALDH1A1MEN1 | |
| SCHEMBL29370031 | 0.73 | GAA (0.51) | GAAALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL6128412 | 0.72 | CYP3A4 (0.44) | ATMKDM4EGAAALDH1A1MEN1 | |
| SCHEMBL16351494 | 0.72 | ABL1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 354 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427468-B2 | PREPARATION OF A METAL COMPLEX | JOHNSON MATTHEY PLC (GB) | 2025-06-04 | — | — | EP | claimed |
| US-12122788-B2 | Process of making CFTR modulators | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2024-10-22 | — | — | US | claimed |
| CN-115872998-B | Preparation method of sildenafil and intermediate thereof | 山东特珐曼药业有限公司 | 2024-09-20 | — | — | CN | claimed |
| US-20230399343-A1 | PROCESS OF MAKING CFTR MODULATORS | VERTEX PHARMACEUTICALS (SAN DIEGO) LLC | 2023-12-14 | — | — | US | claimed |
| EP-4267591-A2 | ORGANOMETALLIC COMPOUNDS | Umicore AG & Co. KG (DE) | 2023-11-01 | — | — | EP | claimed |
| CN-116802187-A | Organometallic compounds | 优米科尔股份公司及两合公司 | 2023-09-22 | — | — | CN | claimed |
| CN-115872998-A | Preparation method of sildenafil and intermediate thereof | 山东特珐曼药业有限公司 | 2023-03-31 | — | — | CN | claimed |
| WO-2022136049-A2 | ORGANOMETALLIC COMPOUNDS | UMICORE AG & CO. KG (DE) | 2022-06-30 | — | — | WO | claimed |
| WO-2017112576-A1 | METHODS FOR EXTERNAL BASE-FREE SUZUKI COUPLINGS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-06-29 | — | — | WO | claimed |
| EP-2427468-B1 | PREPARATION OF A METAL COMPLEX | JOHNSON MATTHEY PLC (GB) | 2017-06-14 | — | — | EP | claimed |
| US-20140051867-A1 | SYNTHESIS OF AN ANTIVIRAL COMPOUND | GILEAD SCIENCES, INC. (US) | 2014-02-20 | — | — | US | claimed |
| US-20140051866-A1 | SYNTHESIS OF AN ANTIVIRAL COMPOUND | GILEAD SCIENCES, INC. (US) | 2014-02-20 | — | — | US | claimed |
| EP-2621893-A1 | PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES | UCB Pharma GmbH (DE) | 2013-08-07 | — | — | EP | claimed |
| WO-2013015456-A1 | METHOD FOR PRODUCING BENZO[B]THIOPHENE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-01-31 | — | — | WO | claimed |
| US-8314232-B2 | Preparation of a quinolinyloxydiphenylcyclopropanedicarboxamide | GLAXOSMITHKLINE LLC (US) | 2012-11-20 | — | — | US | claimed |
| US-20120116109-A1 | PREPARATION OF A METAL COMPLEX | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2012-05-10 | — | — | US | claimed |
| WO-2012041986-A1 | PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES | UCB PHARMA GMBH (DE) | 2012-04-05 | — | — | WO | claimed |
| EP-2427468-A1 | PREPARATION OF A METAL COMPLEX | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2012-03-14 | — | — | EP | claimed |
| WO-2010128316-A1 | PREPARATION OF A METAL COMPLEX | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2010-11-11 | — | — | WO | claimed |
| US-20100081805-A1 | Preparation of a Quinolinyloxydiphenylcyclopropanedicarboxamide | EXELIXIS, INC. | 2010-04-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399343-A1 | PROCESS OF MAKING CFTR MODULATORS | CFTR, SLC26A4, TMEM109 | ATM 1176/4885KDM4E 3960/4885GAA 775/4885 |
| US-20140051867-A1 | SYNTHESIS OF AN ANTIVIRAL COMPOUND | EIF2AK2, SARS1, MAVS | ATM 3176/4885KDM4E 2210/4885GAA 257/4885 |
| US-12122788-B2 | Process of making CFTR modulators | CFTR, SLC26A4, TMEM109 | ATM 1176/4885KDM4E 3960/4885GAA 775/4885 |
| US-20140051866-A1 | SYNTHESIS OF AN ANTIVIRAL COMPOUND | EIF2AK2, SARS1, MAVS | ATM 3121/4885KDM4E 2217/4885GAA 247/4885 |
| US-20120116109-A1 | PREPARATION OF A METAL COMPLEX | PDCD1LG2, CD274, PDCD2L | ATM 1236/4885KDM4E 2792/4885GAA 4147/4885 |
| US-20100081805-A1 | Preparation of a Quinolinyloxydiphenylcyclopropanedicarboxamide | QDPR, CBR3, NQO2 | ATM 2438/4885KDM4E 1032/4885GAA 3658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.