Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 7/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MTOR | P42345 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | HBB | P68871 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | DNMT3B | Q9UBC3 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828970 | 0.88 | DNMT1 (0.35) | DNMT1LMNAMTORSMN1; SMN2ALDH1A1 | |
| SCHEMBL233463 | 0.87 | DNMT1 (0.34) | DNMT1LMNAMTORSMN1; SMN2ALDH1A1 | |
| SCHEMBL1684840 | 0.87 | DNMT1 (0.34) | DNMT1LMNAMTORSMN1; SMN2ALDH1A1 | |
| SCHEMBL2550062 | 0.86 | ALB (0.43) | DNMT1LMNAMTORSMN1; SMN2ALDH1A1 | |
| SCHEMBL29290642 | 0.84 | LMNA (0.35) | DNMT1LMNAMTORSMN1; SMN2ALDH1A1 | |
| SCHEMBL12658357 | 0.78 | LMNA (0.51) | DNMT1LMNAMTORSMN1; SMN2ALDH1A1 | |
| SCHEMBL158512 | 0.78 | LMNA (0.51) | DNMT1LMNAMTORSMN1; SMN2ALDH1A1 | |
| SCHEMBL19506976 | 0.78 | LMNA (0.51) | DNMT1LMNAMTORSMN1; SMN2ALDH1A1 | |
| SCHEMBL27848944 | 0.78 | LMNA (0.51) | DNMT1LMNAMTORSMN1; SMN2ALDH1A1 | |
| Water SCHEMBL28835326 | 0.77 | LMNA (0.50) | DNMT1LMNAMTORSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113330113-A | PDCD-1 homing endonuclease variants | 蓝鸟生物公司 | 2021-08-31 | — | — | CN | disclosed |
| CN-113329760-A | Homing endonuclease variants | 蓝鸟生物公司 | 2021-08-31 | — | — | CN | disclosed |