Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MTOR | P42345 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | HBB | P68871 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828970 | 0.89 | DNMT1 (0.35) | DNMT1LMNAMTORSMN1; SMN2ALDH1A1 | |
| SCHEMBL233463 | 0.88 | DNMT1 (0.34) | DNMT1LMNAMTORSMN1; SMN2ALDH1A1 | |
| SCHEMBL2550062 | 0.87 | ALB (0.43) | DNMT1LMNAMTORSMN1; SMN2ALDH1A1 | |
| SCHEMBL28922015 | 0.87 | DNMT1 (0.34) | DNMT1LMNAMTORSMN1; SMN2ALDH1A1 | |
| SCHEMBL234386 | 0.85 | LMNA (0.34) | DNMT1LMNAMTORSMN1; SMN2ALDH1A1 | |
| SCHEMBL29290642 | 0.85 | LMNA (0.35) | DNMT1LMNAMTORSMN1; SMN2ALDH1A1 | |
| SCHEMBL4428190 | 0.84 | LMNA (0.34) | DNMT1LMNAMTORSMN1; SMN2ALDH1A1 | |
| SCHEMBL17748439 | 0.83 | LMNA (0.33) | DNMT1LMNAMTORSMN1; SMN2ALDH1A1 | |
| SCHEMBL6241745 | 0.82 | LMNA (0.35) | DNMT1LMNAMTORSMN1; SMN2ALDH1A1 | |
| SCHEMBL20500065 | 0.82 | LMNA (0.33) | DNMT1LMNAMTORSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0813539-B1 | IMPROVED PROCESS FOR THE SYNTHESIS OF 2'-O-SUBSTITUTED PYRIMIDINES AND OLIGOMERIC COMPOUNDS THEREFROM | ISIS PHARMACEUTICALS INC (US) | 2006-05-24 | — | — | EP | claimed |
| WO-2023131926-A2 | MODULATION OF HEPATITIS B VIRUS (HBV) EXPRESSION | AUSPER BIOPHARMA CO., LTD. (CN) | 2023-07-13 | — | — | WO | disclosed |
| EP-3997059-A1 | CATIONIC LIPIDS AND USES THEREOF | Factor Bioscience Inc. (US) | 2022-05-18 | — | — | EP | disclosed |
| WO-2021003462-A1 | CATIONIC LIPIDS AND USES THEREOF | FACTOR BIOSCIENCE INC. (US) | 2021-01-07 | — | — | WO | disclosed |
| WO-2011041311-A2 | COMPOSITIONS AND METHODS FOR INHIBITING INFLAMMATION FROM AND REJECTION OF BIOMATERIALS AND OTHER METHODS | YALE UNIVERSITY (US) | 2011-04-07 | — | — | WO | disclosed |