Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MTOR | P42345 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | HBB | P68871 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828970 | 0.89 | DNMT1 (0.35) | DNMT1LMNAMTORSMN1; SMN2ALDH1A1 | |
| SCHEMBL1684840 | 0.88 | DNMT1 (0.34) | DNMT1LMNAMTORSMN1; SMN2ALDH1A1 | |
| SCHEMBL2550062 | 0.87 | ALB (0.43) | DNMT1LMNAMTORSMN1; SMN2ALDH1A1 | |
| SCHEMBL28922015 | 0.87 | DNMT1 (0.34) | DNMT1LMNAMTORSMN1; SMN2ALDH1A1 | |
| SCHEMBL29290642 | 0.85 | LMNA (0.35) | DNMT1LMNAMTORSMN1; SMN2ALDH1A1 | |
| SCHEMBL25243184 | 0.83 | ADSS2 (0.40) | SMN1; SMN2PDE4DPDE3A | |
| SCHEMBL158512 | 0.79 | LMNA (0.51) | DNMT1LMNAMTORSMN1; SMN2ALDH1A1 | |
| SCHEMBL12658357 | 0.79 | LMNA (0.51) | DNMT1LMNAMTORSMN1; SMN2ALDH1A1 | |
| SCHEMBL27848944 | 0.79 | LMNA (0.51) | DNMT1LMNAMTORSMN1; SMN2ALDH1A1 | |
| SCHEMBL19506976 | 0.79 | LMNA (0.51) | DNMT1LMNAMTORSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113195720-A | Enzymatic RNA synthesis | 哈佛大学的校长及成员们 | 2021-07-30 | — | — | CN | claimed |
| CN-118829423-A | Compositions for delivery of payload molecules to airway epithelium | 摩登纳特斯有限公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-118019526-A | Methods for preparing lipid nanoparticle compositions for delivery of payload molecules to airway epithelium | 摩登纳特斯有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-118019527-A | Method for preparing lipid nanoparticle compositions | 摩登纳特斯有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-116348147-A | Compositions for delivery of payload molecules to airway epithelium | 摩登纳特斯有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-116133652-A | Method for preparing lipid nanoparticles | 摩登纳特斯有限公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-113195720-A | Enzymatic RNA synthesis | 哈佛大学的校长及成员们 | 2021-07-30 | — | — | CN | disclosed |
| CN-109803977-A | NUCLEIC ACID PRODUCTS AND METHODS OF ADMINISTRATION THEREOF | 菲克特生物科学股份有限公司 | 2019-05-24 | — | — | CN | disclosed |
| CN-105940110-A | Methods and products for nucleic acid production and delivery | 菲克特生物科学股份有限公司 | 2016-09-14 | — | — | CN | disclosed |
| US-8206935-B2 | Method of rapidly quantifying hydroxymethylated DNA | LI WEIWEI (US) | 2012-06-26 | — | — | US | disclosed |
| US-20120122087-A1 | 5-Hydroxymethylcytosine as a biomarker for early detection, treatment and prognostic monitoring of cancer | LI WEIWEI (US) | 2012-05-17 | — | — | US | disclosed |
| US-20120107808-A1 | High throughput detection of gene-specific hydroxymethylation | LI WEIWEI (US) | 2012-05-03 | — | — | US | disclosed |
| US-20120003663-A1 | Method of rapidly quantifying hydroxymethylated DNA | LI WEIWEI (US) | 2012-01-05 | — | — | US | disclosed |