Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.33 |
| ▸ | MTOR | P42345 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828970 | 0.86 | DNMT1 (0.35) | LMNASMN1; SMN2ALDH1A1POLBPDE4D | |
| SCHEMBL233463 | 0.85 | DNMT1 (0.34) | LMNASMN1; SMN2ALDH1A1POLBPDE4D | |
| SCHEMBL1684840 | 0.85 | DNMT1 (0.34) | LMNASMN1; SMN2ALDH1A1POLBPDE4D | |
| SCHEMBL30358621 | 0.84 | LMNA (0.35) | LMNASMN1; SMN2ALDH1A1POLBPDE4D | |
| SCHEMBL28922015 | 0.84 | DNMT1 (0.34) | LMNASMN1; SMN2ALDH1A1POLBPDE4D | |
| SCHEMBL2550062 | 0.84 | ALB (0.43) | LMNASMN1; SMN2ALDH1A1POLBPDE4D | |
| SCHEMBL158512 | 0.76 | LMNA (0.51) | LMNASMN1; SMN2ALDH1A1POLBPDE4D | |
| SCHEMBL27848944 | 0.76 | LMNA (0.51) | LMNASMN1; SMN2ALDH1A1POLBPDE4D | |
| SCHEMBL12658357 | 0.76 | LMNA (0.51) | LMNASMN1; SMN2ALDH1A1POLBPDE4D | |
| SCHEMBL19506976 | 0.76 | LMNA (0.51) | LMNASMN1; SMN2ALDH1A1POLBPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109640946-A | Negative feedback regulation of HIV-1 by gene editing strategies | 天普大学-联邦高等教育系统 | 2019-04-16 | — | — | CN | disclosed |