Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | STAT1 | P42224 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 6/20 | 0.52 |
| ▸ | BCHE | P06276 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26768339 | 0.92 | KDM4E (0.55) | KDM4EALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL7758792 | 0.91 | KDM4E (0.60) | KDM4EALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL29894593 | 0.84 | KDM4E (0.76) | KDM4EALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL28627763 | 0.84 | KDM4E (0.76) | KDM4EALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL28629168 | 0.84 | ACHE (0.67) | KDM4EALDH1A1MAPTACHEBCHE | |
| SCHEMBL29894611 | 0.84 | ACHE (0.67) | KDM4EALDH1A1MAPTACHEBCHE | |
| SCHEMBL26768331 | 0.83 | PDE2A (0.61) | KDM4EALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL26768333 | 0.83 | KDM4E (0.54) | KDM4EALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL26766710 | 0.81 | KDM4E (0.57) | KDM4EALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL26766708 | 0.81 | KDM4E (0.54) | KDM4EALDH1A1RAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113336735-B | Urolithin compound, preparation method, pharmaceutical composition and application | 常州大学 | 2022-09-30 | — | — | CN | disclosed |
| CN-113336735-A | Urolithin compound, preparation method, pharmaceutical composition and application | 常州大学 | 2021-09-03 | — | — | CN | disclosed |