Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | XDH | P47989 | 2/20 | 0.57 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.56 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | STAT1 | P42224 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL805441 | 0.95 | MAPT (0.69) | PDE2AMAPTXDHMAP1LC3BMAP1LC3A | |
| SCHEMBL7758792 | 0.86 | KDM4E (0.60) | MAPTALDH1A1RAB9AKDM4ENPC1 | |
| SCHEMBL29894593 | 0.85 | KDM4E (0.76) | MAPTALDH1A1RAB9AKDM4ENPC1 | |
| SCHEMBL28627763 | 0.85 | KDM4E (0.76) | MAPTALDH1A1RAB9AKDM4ENPC1 | |
| SCHEMBL26766591 | 0.85 | MAPT (0.63) | PDE2AMAPTXDHMAP1LC3BMAP1LC3A | |
| SCHEMBL29894611 | 0.85 | ACHE (0.67) | MAPTALDH1A1KDM4EKMT2AL3MBTL1 | |
| SCHEMBL28629168 | 0.85 | ACHE (0.67) | MAPTALDH1A1KDM4EKMT2AL3MBTL1 | |
| SCHEMBL26768333 | 0.84 | KDM4E (0.54) | MAPTALDH1A1RAB9AKDM4ENPC1 | |
| SCHEMBL8868179 | 0.84 | XDH (0.77) | MAPTXDHMAP1LC3BMAP1LC3AALDH1A1 | |
| SCHEMBL28922154 | 0.83 | KDM4E (0.52) | MAPTALDH1A1RAB9AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11820751-B2 | Urolithin derivatives and methods of use thereof | VANDRIA SA (CH) | 2023-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11820751-B2 | Urolithin derivatives and methods of use thereof | NLN, UQCRC2, TUFM | PDE2A 1089/4885MAPT 217/4885XDH 88/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.