Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.47 |
| ▸ | HTR2B | P41595 | 7/20 | 0.47 |
| ▸ | HTR2A | P28223 | 6/20 | 0.47 |
| ▸ | ACHE | P22303 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22318255 | 0.78 | LMNA (0.34) | HTR2AKMT2ATSHRGAA | |
| SCHEMBL15041795 | 0.77 | HTR2C (0.53) | HTR2CHTR2BHTR2AACHEKMT2A | |
| SCHEMBL28922579 | 0.76 | HTR2C (0.49) | HTR2CHTR2BHTR2AACHEKMT2A | |
| SCHEMBL28749727 | 0.75 | DRD2 (0.41) | HTR2CHTR2BHTR2AKCNH2 | |
| SCHEMBL10851353 | 0.75 | CAPN1 (0.53) | HTR2CHTR2BHTR2AACHEOPRM1 | |
| SCHEMBL8498091 | 0.75 | CAPN1 (0.53) | HTR2CHTR2BHTR2AACHEOPRM1 | |
| SCHEMBL10346073 | 0.73 | HTR2C (0.47) | HTR2CHTR2BHTR2AACHEKMT2A | |
| SCHEMBL8782404 | 0.73 | NPC1 (0.51) | KMT2ANPC1PKMRAB9ATSHR | |
| SCHEMBL10854074 | 0.72 | CAPN1 (0.56) | HTR2CHTR2BHTR2AACHETSHR | |
| SCHEMBL10855534 | 0.72 | CAPN1 (0.56) | HTR2CHTR2BHTR2AACHETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115397412-A | Modulators of MAS-related G protein receptor X4 and related products and methods | 伊赛恩特制药公司 | 2022-11-25 | — | — | CN | disclosed |