SCHEMBL28924232

SCHEMBL28924232

CCNc1ccccc1.N#CCC#N

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.48
ADRA2A P08913 2/20 0.42
MAPT P10636 3/20 0.41
ALDH1A1 P00352 1/20 0.41
ADORA2A P29274 1/20 0.41
ADORA1 P30542 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.37
NPC1 O15118 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2C19 P33261 1/20 0.37
RAB9A P51151 1/20 0.37
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36
GAA P10253 2/20 0.36
TSHR P16473 3/20 0.36
CDK1 P06493 1/20 0.36
CDK2 P24941 1/20 0.36
KDM4E B2RXH2 1/20 0.35
HPGD P15428 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetonitrile SCHEMBL6671979 0.87 LMNA (0.52) LMNAADRA2AMAPTALDH1A1ADORA2A
Water SCHEMBL9462188 0.87 LMNA (0.59) LMNAADRA2AMAPTALDH1A1L3MBTL1
SCHEMBL20852333 0.84 LMNA (0.61) LMNAADRA2AMAPTALDH1A1L3MBTL1
SCHEMBL7709 0.84
SCHEMBL4916223 0.84 LMNA (0.61) LMNAADRA2AMAPTALDH1A1L3MBTL1
Nitrogen SCHEMBL11864887 0.82 LMNA (0.55) LMNAADRA2AMAPTALDH1A1L3MBTL1
Cyanide SCHEMBL28138043 0.82 LMNA (0.55) LMNAADRA2AMAPTALDH1A1L3MBTL1
Ammonia Solution, Strong SCHEMBL8429752 0.82 LMNA (0.59) LMNAADRA2AMAPTALDH1A1L3MBTL1
Ethane SCHEMBL29007244 0.82 LMNA (0.59) LMNAADRA2AMAPTALDH1A1L3MBTL1
Iodide SCHEMBL17710408 0.82 LMNA (0.59) LMNAADRA2AMAPTALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113444031-A Synthetic method of 2, 2-diaryl acetonitrile compound 兰州大学 2021-09-28 CN disclosed