Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL9462188 | 0.91 | LMNA (0.59) | LMNAADRA2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL20852333 | 0.88 | LMNA (0.61) | LMNAADRA2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL7709 | 0.88 | — | — | |
| SCHEMBL4916223 | 0.88 | LMNA (0.61) | LMNAADRA2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL28924232 | 0.87 | LMNA (0.48) | LMNAADRA2AMAPTALDH1A1ADORA2A | |
| Nitrogen SCHEMBL11864887 | 0.86 | LMNA (0.55) | LMNAADRA2AMAPTALDH1A1L3MBTL1 | |
| Cyanide SCHEMBL28138043 | 0.86 | LMNA (0.55) | LMNAADRA2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL9573532 | 0.85 | LMNA (0.59) | LMNAADRA2AMAPTALDH1A1L3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL8429752 | 0.85 | LMNA (0.59) | LMNAADRA2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL29961278 | 0.85 | LMNA (0.59) | LMNAADRA2AMAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1174419-B1 | A method for producing an alpha-aminonitrile from a tertiary amine and a cyanide through oxidation with oxygen by using a transition metal catalyst | UNIV OSAKA (JP) | 2004-10-06 | — | — | EP | disclosed |
| US-6486340-B2 | Method for producing an α-aminonitrile from a tertiary anime and a cyanide through oxidation with oxygen by using a transition metal catalyst | OSAKA UNIVERSITY (JP) | 2002-11-26 | — | — | US | disclosed |
| US-20020042534-A1 | Method for producing an alpha-aminonitrile from a tertiary anime and a cyanide through oxidation with oxygen by using a transition metal catalyst | OSAKA UNIVERSITY (JP) | 2002-04-11 | — | — | US | disclosed |
| EP-1174419-A1 | A method for producing an alpha-aminonitrile from a tertiary amine and a cyanide through oxidation with oxygen by using a transition metal catalyst | OSAKA UNIVERSITY (JP) | 2002-01-23 | — | — | EP | disclosed |