Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1536541 | 0.85 | LMNA (0.46) | LMNAALOX5SLC22A6AKR1B1TSHR | |
| SCHEMBL23533413 | 0.83 | TSHR (0.48) | LMNAALOX5SLC22A6TSHRNFKB1 | |
| SCHEMBL10924973 | 0.75 | — | — | |
| SCHEMBL16084399 | 0.75 | — | — | |
| SCHEMBL14465121 | 0.73 | ALDH1A1 (0.31) | UGT2B7TSHR | |
| SCHEMBL5691355 | 0.70 | UGT2B7 (0.36) | UGT2B7FOLH1 | |
| Bicarbonate SCHEMBL11272732 | 0.70 | APLNR (0.39) | LMNAFFAR3APLNRGRM2GRM5 | |
| SCHEMBL16060618 | 0.69 | — | — | |
| SCHEMBL16134934 | 0.69 | — | — | |
| SCHEMBL13409658 | 0.69 | ALDH1A1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286073-A1 | COMPOUNDS AND METHODS FOR PHARMACEUTICAL USE | GENERICS (UK) LIMITED (GB) | 2010-11-11 | — | — | US | claimed |
| EP-2205229-A1 | COMPOUNDS AND METHODS FOR PHARMACEUTICAL USE | Mintails Limited (CY) | 2010-07-14 | — | — | EP | claimed |
| WO-2009044202-A1 | COMPOUNDS AND METHODS FOR PHARMACEUTICAL USE | MINTAILS LIMITED (CY) | 2009-04-09 | — | — | WO | claimed |
| US-20100286073-A1 | COMPOUNDS AND METHODS FOR PHARMACEUTICAL USE | GENERICS (UK) LIMITED (GB) | 2010-11-11 | — | — | US | disclosed |
| EP-2205229-A1 | COMPOUNDS AND METHODS FOR PHARMACEUTICAL USE | Mintails Limited (CY) | 2010-07-14 | — | — | EP | disclosed |
| WO-2009044202-A1 | COMPOUNDS AND METHODS FOR PHARMACEUTICAL USE | MINTAILS LIMITED (CY) | 2009-04-09 | — | — | WO | disclosed |