Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 2/20 | 0.31 |
| ▸ | GABRD | O14764 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.31 |
| ▸ | GABRE | P78334 | 2/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.31 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.31 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.31 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2892528 | 0.73 | UGT2B7 (0.39) | TSHRUGT2B7 | |
| SCHEMBL27620538 | 0.65 | SLC22A6 (0.36) | SMN1; SMN2CYP1A2MAPTUGT2B7 | |
| SCHEMBL8097536 | 0.63 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2MAPTCYP3A4TSHR | |
| SCHEMBL22963815 | 0.62 | MME (0.35) | ALDH1A1SMN1; SMN2CYP1A2TSHRUGT2B7 | |
| SCHEMBL13756314 | 0.61 | SLC22A6 (0.36) | ALDH1A1SMN1; SMN2GABRPGABRDGABRA1 | |
| SCHEMBL1536541 | 0.61 | LMNA (0.46) | ALDH1A1TSHR | |
| SCHEMBL25118413 | 0.60 | GPR84 (0.35) | MAPT | |
| SCHEMBL23533413 | 0.59 | TSHR (0.48) | ALDH1A1TSHR | |
| SCHEMBL15618969 | 0.59 | APLNR (0.46) | MAPTTSHR | |
| Succinic Acid SCHEMBL8366457 | 0.58 | LMNA (0.53) | ALDH1A1GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007084319-A2 | DIARYL PIPERIDINES AS CB1 MODULATORS | SCHERING CORPORATION (US) | 2007-07-26 | — | — | WO | disclosed |