Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.53 |
| ▸ | PRMT5 | O14744 | 11/20 | 0.50 |
| ▸ | WDR77 | Q9BQA1 | 9/20 | 0.50 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28928596 | 0.91 | DRD2 (0.44) | DRD2PRMT5WDR77CARM1POLB | |
| SCHEMBL28654076 | 0.85 | HDAC4 (0.42) | DRD2PRMT5WDR77 | |
| SCHEMBL28654413 | 0.81 | CARM1 (0.51) | PRMT5WDR77CARM1POLB | |
| SCHEMBL28654411 | 0.81 | CARM1 (0.51) | PRMT5WDR77CARM1POLB | |
| SCHEMBL28650972 | 0.77 | TDP1 (0.57) | — | |
| SCHEMBL18215162 | 0.76 | DRD2 (0.57) | DRD2PRMT5WDR77CARM1POLB | |
| SCHEMBL29758953 | 0.76 | DRD2 (0.57) | DRD2PRMT5WDR77CARM1POLB | |
| SCHEMBL28670702 | 0.76 | DRD2 (0.57) | DRD2PRMT5WDR77CARM1POLB | |
| SCHEMBL28650984 | 0.76 | NPSR1 (0.44) | POLB | |
| SCHEMBL28669034 | 0.74 | NPSR1 (0.51) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107735088-B | Histone deacetylase inhibitors, compositions and methods of use thereof | CHDI基金会股份有限公司 | 2021-11-02 | — | — | CN | disclosed |