Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | VIP | P01282 | 1/20 | 0.35 |
| ▸ | KCNA6 | P17658 | 1/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | KCNA4 | P22459 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28928850 | 0.85 | PKM (0.44) | PKMCREBBPHRH3ADRA2AADRA1D | |
| SCHEMBL28928845 | 0.84 | NPC1 (0.40) | MTNR1AMTNR1BLMNA | |
| SCHEMBL28928825 | 0.80 | DAO (0.42) | PKMCREBBPHRH3ADRA2AADRA1D | |
| SCHEMBL28928828 | 0.77 | DAO (0.39) | PKMCREBBPHRH3ADRA2AADRA1D | |
| SCHEMBL28929188 | 0.77 | PKM (0.42) | PKMCREBBPHRH3ADRA2AADRA1D | |
| SCHEMBL28962238 | 0.76 | PKM (0.47) | PKMCREBBPHRH3DAOMTNR1A | |
| SCHEMBL28962239 | 0.74 | DAO (0.46) | PKMCREBBPHRH3ADRA2AADRA1D | |
| SCHEMBL28928834 | 0.72 | PKM (0.50) | PKMCREBBPHRH3DAOVIP | |
| SCHEMBL28962240 | 0.71 | DAO (0.42) | PKMCREBBPHRH3ADRA2AADRA1D | |
| SCHEMBL28928851 | 0.70 | PKM (0.53) | PKMCREBBPHRH3ADRA2AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583942-A | 2-substituted 5-phenyl-oxazole derivative, preparation method thereof and application thereof as MNK (MNK) inhibitor | 中国海洋大学 | 2023-01-10 | — | — | CN | disclosed |