Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | VIP | P01282 | 1/20 | 0.40 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.39 |
| ▸ | KCNA6 | P17658 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | KCNA4 | P22459 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28928851 | 0.91 | PKM (0.53) | PKMCREBBPDAONPC1RAB9A | |
| SCHEMBL28928861 | 0.87 | PKM (0.50) | PKMCREBBPDAONPC1RAB9A | |
| SCHEMBL28962238 | 0.84 | PKM (0.47) | PKMCREBBPDAOSMN1; SMN2HTT | |
| SCHEMBL28929186 | 0.84 | PKM (0.47) | PKMCREBBPDAONPC1RAB9A | |
| SCHEMBL28928850 | 0.80 | PKM (0.44) | PKMCREBBPDAONPC1RAB9A | |
| SCHEMBL28928872 | 0.77 | LMNA (0.62) | NPC1RAB9ASMN1; SMN2KDM4ETAAR1 | |
| SCHEMBL28928854 | 0.76 | PKM (0.52) | PKMCREBBPDAONPC1RAB9A | |
| SCHEMBL28929188 | 0.76 | PKM (0.42) | PKMCREBBPDAOEGFRERBB2 | |
| SCHEMBL28928857 | 0.72 | DAO (0.48) | PKMCREBBPDAOVIPKCNA6 | |
| SCHEMBL28929179 | 0.72 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2KDM4ETAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583942-A | 2-substituted 5-phenyl-oxazole derivative, preparation method thereof and application thereof as MNK (MNK) inhibitor | 中国海洋大学 | 2023-01-10 | — | — | CN | disclosed |