Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | VIP | P01282 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | KCNA6 | P17658 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | KCNA4 | P22459 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28928861 | 0.91 | PKM (0.50) | PKMCREBBPDAONPC1RAB9A | |
| SCHEMBL28928834 | 0.91 | PKM (0.50) | PKMCREBBPDAONPC1RAB9A | |
| SCHEMBL28962238 | 0.87 | PKM (0.47) | PKMCREBBPDAOSMN1; SMN2KDM4E | |
| SCHEMBL28929186 | 0.87 | PKM (0.47) | PKMCREBBPDAONPC1RAB9A | |
| SCHEMBL28928850 | 0.84 | PKM (0.44) | PKMCREBBPDAONPC1RAB9A | |
| SCHEMBL28929179 | 0.81 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2KDM4ETAAR1 | |
| SCHEMBL28929188 | 0.79 | PKM (0.42) | PKMCREBBPDAOVIPEGFR | |
| SCHEMBL28928838 | 0.74 | PKM (0.56) | PKMCREBBPDAOVIPKCNA6 | |
| SCHEMBL17373696 | 0.74 | BCAT2 (0.51) | NPC1RAB9ASMN1; SMN2KDM4ETAAR1 | |
| SCHEMBL1554808 | 0.74 | BCAT2 (0.51) | NPC1RAB9ASMN1; SMN2KDM4ETAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583942-A | 2-substituted 5-phenyl-oxazole derivative, preparation method thereof and application thereof as MNK (MNK) inhibitor | 中国海洋大学 | 2023-01-10 | — | — | CN | disclosed |