Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28928851 | 0.87 | PKM (0.53) | PKMCREBBPDAOHRH3ADRA2A | |
| SCHEMBL28928861 | 0.84 | PKM (0.50) | PKMCREBBPDAOHRH3ADRA2A | |
| SCHEMBL28928834 | 0.84 | PKM (0.50) | PKMCREBBPL3MBTL1DAOHRH3 | |
| SCHEMBL28962238 | 0.83 | PKM (0.47) | PKMCREBBPALDH1A1KMT2AMAPT | |
| SCHEMBL28928850 | 0.80 | PKM (0.44) | PKMCREBBPALDH1A1DAOHRH3 | |
| SCHEMBL28928827 | 0.79 | CYP1A2 (0.46) | ALDH1A1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL28928863 | 0.78 | DAO (0.49) | PKMCREBBPALDH1A1MEN1KMT2A | |
| SCHEMBL28929188 | 0.76 | PKM (0.42) | PKMCREBBPALDH1A1DAOHRH3 | |
| SCHEMBL28928865 | 0.74 | DAO (0.46) | PKMCREBBPALDH1A1MEN1KMT2A | |
| SCHEMBL28929179 | 0.69 | NPC1 (0.47) | LMNANPC1RAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583942-A | 2-substituted 5-phenyl-oxazole derivative, preparation method thereof and application thereof as MNK (MNK) inhibitor | 中国海洋大学 | 2023-01-10 | — | — | CN | disclosed |