Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28929404 | 0.87 | NPC1 (0.62) | POLBNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL28928872 | 0.86 | LMNA (0.62) | POLBNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL28929179 | 0.86 | NPC1 (0.47) | POLBNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL28928818 | 0.83 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL28928827 | 0.83 | CYP1A2 (0.46) | POLBNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL28928862 | 0.79 | KDM4E (0.41) | POLBNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL28928861 | 0.77 | PKM (0.50) | NPC1RAB9ASMN1; SMN2KDM4ETAAR1 | |
| SCHEMBL28928830 | 0.74 | MEN1 (0.64) | POLBNPC1RAB9ASMN1; SMN2ATM | |
| SCHEMBL13840109 | 0.74 | KDM4E (0.56) | POLBKMT2AHSD17B10KDM4ELMNA | |
| SCHEMBL14830283 | 0.74 | BCAT2 (0.51) | NPC1RAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583942-A | 2-substituted 5-phenyl-oxazole derivative, preparation method thereof and application thereof as MNK (MNK) inhibitor | 中国海洋大学 | 2023-01-10 | — | — | CN | disclosed |