Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28929404 | 0.84 | NPC1 (0.62) | KDM4EL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28928843 | 0.83 | POLB (0.50) | KDM4EMEN1KMT2ANPC1RAB9A | |
| SCHEMBL28929179 | 0.83 | NPC1 (0.47) | CYP1A2CYP2D6KDM4ENPC1RAB9A | |
| SCHEMBL28928872 | 0.83 | LMNA (0.62) | KDM4ENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL28928818 | 0.82 | NPC1 (0.51) | CYP1A2CYP2D6KDM4EALDH1A1MAPT | |
| SCHEMBL28929186 | 0.79 | PKM (0.47) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28928862 | 0.78 | KDM4E (0.41) | KDM4ENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL28928841 | 0.76 | CYP1A2 (0.48) | CYP1A2CYP2D6KDM4EMEN1KMT2A | |
| SCHEMBL13840109 | 0.74 | KDM4E (0.56) | KDM4EKMT2ALMNAPOLB | |
| SCHEMBL28929413 | 0.73 | GAA (0.45) | KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583942-A | 2-substituted 5-phenyl-oxazole derivative, preparation method thereof and application thereof as MNK (MNK) inhibitor | 中国海洋大学 | 2023-01-10 | — | — | CN | disclosed |