Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28928832 | 0.87 | NPC1 (0.45) | GAAKDM4ENPC1RAB9ALMNA | |
| SCHEMBL28928821 | 0.84 | GAA (0.47) | GAAKDM4ENPC1RAB9ALMNA | |
| SCHEMBL28928836 | 0.82 | KDM4E (0.43) | GAAKDM4ELMNAPOLB | |
| SCHEMBL28928858 | 0.81 | NPC1 (0.44) | GAAKDM4ENPC1RAB9ALMNA | |
| SCHEMBL28929181 | 0.78 | AOC3 (0.43) | GAAKDM4EL3MBTL1NPC1RAB9A | |
| SCHEMBL28929418 | 0.77 | NPC1 (0.59) | GAAKDM4EL3MBTL1NPC1RAB9A | |
| SCHEMBL28928859 | 0.76 | POLB (0.52) | GAAKDM4ERAB9AALDH1A1LMNA | |
| SCHEMBL1548903 | 0.73 | KMT2A (0.50) | L3MBTL1NPC1RAB9AHTTLMNA | |
| SCHEMBL3069825 | 0.72 | MRGPRX4 (0.56) | KDM4EL3MBTL1NPC1RAB9AALDH1A1 | |
| SCHEMBL2780003 | 0.71 | HTR1A (0.47) | NPC1RAB9AALDH1A1POLBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583942-A | 2-substituted 5-phenyl-oxazole derivative, preparation method thereof and application thereof as MNK (MNK) inhibitor | 中国海洋大学 | 2023-01-10 | — | — | CN | disclosed |