Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28928832 | 0.85 | NPC1 (0.45) | GAAKDM4EKMT2ALMNANPC1 | |
| SCHEMBL28928852 | 0.84 | GAA (0.42) | GAAKDM4ELMNANPC1RAB9A | |
| SCHEMBL28928839 | 0.82 | DAO (0.44) | HRH3KMT2AITGB3ITGA2B | |
| SCHEMBL28928836 | 0.82 | KDM4E (0.43) | GAAHRH3KDM4EKMT2ALMNA | |
| SCHEMBL28929413 | 0.78 | GAA (0.45) | GAAHRH3KDM4ELMNA | |
| SCHEMBL28929418 | 0.77 | NPC1 (0.59) | GAAKDM4EKMT2ANPC1RAB9A | |
| SCHEMBL28928858 | 0.75 | NPC1 (0.44) | GAAKDM4ELMNANPC1MAPT | |
| SCHEMBL28928859 | 0.73 | POLB (0.52) | GAAKDM4ELMNARAB9A | |
| SCHEMBL28928823 | 0.72 | LMNA (0.65) | KDM4EKMT2ALMNANPC1MAPT | |
| SCHEMBL28928830 | 0.72 | MEN1 (0.64) | GAAKDM4EKMT2ALMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583942-A | 2-substituted 5-phenyl-oxazole derivative, preparation method thereof and application thereof as MNK (MNK) inhibitor | 中国海洋大学 | 2023-01-10 | — | — | CN | disclosed |