Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28928862 | 0.88 | KDM4E (0.41) | GAAKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28929413 | 0.85 | GAA (0.45) | GAAKDM4E | |
| SCHEMBL28928831 | 0.83 | KDM4E (0.42) | GAAKDM4E | |
| SCHEMBL28928845 | 0.82 | NPC1 (0.40) | GAAKDM4ENPC1RAB9A | |
| SCHEMBL28928818 | 0.78 | NPC1 (0.51) | AOC3GAAKDM4ENPC1RAB9A | |
| SCHEMBL28928852 | 0.78 | GAA (0.42) | GAAKDM4EL3MBTL1NPC1RAB9A | |
| SCHEMBL28929404 | 0.77 | NPC1 (0.62) | KDM4EL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15075024 | 0.76 | AOC3 (0.45) | AOC3L3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3070382 | 0.76 | HIF1A (0.56) | AOC3GAAKDM4EL3MBTL1RAB9A | |
| SCHEMBL6978184 | 0.71 | AOC3 (0.48) | AOC3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583942-A | 2-substituted 5-phenyl-oxazole derivative, preparation method thereof and application thereof as MNK (MNK) inhibitor | 中国海洋大学 | 2023-01-10 | — | — | CN | disclosed |