Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.38 |
| ▸ | VIP | P01282 | 1/20 | 0.36 |
| ▸ | KCNA6 | P17658 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
| ▸ | KCNA4 | P22459 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28928840 | 0.88 | PKM (0.51) | DAOPKMCREBBPHRH3ADRA2A | |
| SCHEMBL28928863 | 0.86 | DAO (0.49) | DAOPKMCREBBPHRH3ADRA2A | |
| SCHEMBL28928857 | 0.85 | DAO (0.48) | DAOPKMCREBBPHRH3ADRA2A | |
| SCHEMBL28929420 | 0.85 | DAO (0.48) | DAOPKMCREBBPHRH3VIP | |
| SCHEMBL28928874 | 0.84 | DAO (0.46) | DAOPKMCREBBPHRH3ALDH1A1 | |
| SCHEMBL28962240 | 0.81 | DAO (0.42) | DAOPKMCREBBPHRH3ADRA2A | |
| SCHEMBL28929186 | 0.74 | PKM (0.47) | DAOPKMCREBBPHRH3ADRA2A | |
| SCHEMBL28928838 | 0.72 | PKM (0.56) | DAOPKMCREBBPHRH3ADRA2A | |
| SCHEMBL28929419 | 0.69 | PKM (0.52) | DAOPKMCREBBPVIPKCNA6 | |
| SCHEMBL28746425 | 0.68 | CREBBP (0.60) | DAOPKMCREBBPHRH3ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583942-A | 2-substituted 5-phenyl-oxazole derivative, preparation method thereof and application thereof as MNK (MNK) inhibitor | 中国海洋大学 | 2023-01-10 | — | — | CN | disclosed |