Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | NQO2 | P16083 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28929184 | 0.88 | RAB9A (0.53) | RAB9APKMALDH1A1KMT2AMEN1 | |
| SCHEMBL28928867 | 0.83 | KMT2A (0.60) | RAB9APKMALDH1A1KMT2ALMNA | |
| SCHEMBL28928817 | 0.83 | POLB (0.55) | RAB9APKMALDH1A1KMT2AMEN1 | |
| SCHEMBL28929417 | 0.83 | SMN1; SMN2 (0.55) | RAB9APKMALDH1A1KMT2AMEN1 | |
| SCHEMBL26644596 | 0.80 | ALDH1A1 (0.68) | RAB9AALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL30644009 | 0.79 | NPC1 (0.72) | RAB9AALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL31232828 | 0.79 | NPC1 (0.72) | RAB9AALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL28928844 | 0.76 | ALDH1A1 (0.62) | RAB9APKMALDH1A1KMT2AMEN1 | |
| SCHEMBL23521348 | 0.76 | ALDH1A1 (0.60) | RAB9APKMALDH1A1KMT2AMEN1 | |
| SCHEMBL7044792 | 0.76 | AOC3 (0.63) | RAB9AALDH1A1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583942-A | 2-substituted 5-phenyl-oxazole derivative, preparation method thereof and application thereof as MNK (MNK) inhibitor | 中国海洋大学 | 2023-01-10 | — | — | CN | disclosed |