Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.38 |
| ▸ | VIP | P01282 | 1/20 | 0.38 |
| ▸ | KCNA6 | P17658 | 1/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.37 |
| ▸ | KCNA4 | P22459 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28962239 | 0.87 | DAO (0.46) | DAOPKMHRH3ADRA2AADRA1D | |
| SCHEMBL28928821 | 0.82 | GAA (0.47) | HRH3ITGB3ITGA2BKMT2A | |
| SCHEMBL28928873 | 0.79 | DAO (0.49) | DAOPKMCREBBPALDH1A1KMT2A | |
| SCHEMBL28929188 | 0.79 | PKM (0.42) | DAOPKMHRH3ADRA2AADRA1D | |
| SCHEMBL28928838 | 0.78 | PKM (0.56) | DAOPKMHRH3ADRA2AADRA1D | |
| SCHEMBL28962240 | 0.77 | DAO (0.42) | DAOPKMHRH3ADRA2AADRA1D | |
| SCHEMBL28928825 | 0.76 | DAO (0.42) | DAOPKMHRH3ADRA2AADRA1D | |
| SCHEMBL28929419 | 0.75 | PKM (0.52) | DAOPKMCREBBPALDH1A1VIP | |
| SCHEMBL28928854 | 0.75 | PKM (0.52) | DAOPKMHRH3CREBBPALDH1A1 | |
| SCHEMBL28928863 | 0.75 | DAO (0.49) | DAOPKMHRH3ADRA2AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583942-A | 2-substituted 5-phenyl-oxazole derivative, preparation method thereof and application thereof as MNK (MNK) inhibitor | 中国海洋大学 | 2023-01-10 | — | — | CN | disclosed |