Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28928862 | 0.83 | KDM4E (0.41) | KDM4EGAALMNAPOLB | |
| SCHEMBL28929181 | 0.83 | AOC3 (0.43) | KDM4EGAA | |
| SCHEMBL28929413 | 0.83 | GAA (0.45) | KDM4EGAALMNAHRH3 | |
| SCHEMBL28928836 | 0.80 | KDM4E (0.43) | KDM4EGAALMNAPTPN1POLB | |
| SCHEMBL28928845 | 0.76 | NPC1 (0.40) | KDM4EGAALMNAPOLB | |
| SCHEMBL28928818 | 0.76 | NPC1 (0.51) | KDM4EGAALMNA | |
| SCHEMBL28929404 | 0.74 | NPC1 (0.62) | KDM4ELMNAPOLB | |
| SCHEMBL28928872 | 0.71 | LMNA (0.62) | KDM4ELMNAPOLB | |
| SCHEMBL28929179 | 0.71 | NPC1 (0.47) | KDM4ELMNAPOLB | |
| SCHEMBL28928843 | 0.71 | POLB (0.50) | KDM4EGAALMNAPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583942-A | 2-substituted 5-phenyl-oxazole derivative, preparation method thereof and application thereof as MNK (MNK) inhibitor | 中国海洋大学 | 2023-01-10 | — | — | CN | disclosed |