Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28928862 | 0.85 | KDM4E (0.41) | GAAKDM4ELMNA | |
| SCHEMBL28929181 | 0.85 | AOC3 (0.43) | GAAKDM4E | |
| SCHEMBL28929188 | 0.83 | PKM (0.42) | HRH3LMNAALDH1A1CYP3A4HIF1A | |
| SCHEMBL28928831 | 0.83 | KDM4E (0.42) | GAAHRH3KDM4ELMNA | |
| SCHEMBL28928818 | 0.78 | NPC1 (0.51) | GAAKDM4ELMNAALDH1A1 | |
| SCHEMBL28928821 | 0.78 | GAA (0.47) | GAAHRH3KDM4ELMNA | |
| SCHEMBL28929404 | 0.74 | NPC1 (0.62) | KDM4ELMNA | |
| SCHEMBL28928872 | 0.74 | LMNA (0.62) | KDM4ELMNA | |
| SCHEMBL28928843 | 0.74 | POLB (0.50) | GAAKDM4ELMNA | |
| SCHEMBL28929179 | 0.74 | NPC1 (0.47) | KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583942-A | 2-substituted 5-phenyl-oxazole derivative, preparation method thereof and application thereof as MNK (MNK) inhibitor | 中国海洋大学 | 2023-01-10 | — | — | CN | disclosed |