SCHEMBL289313

SCHEMBL289313

O=CC=Cc1ccccc1C=O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.65
KMT2A Q03164 3/20 0.65
MEN1 O00255 2/20 0.65
THRB P10828 1/20 0.65
BLM P54132 1/20 0.65
TDP1 Q9NUW8 1/20 0.65
CDK4 P11802 4/20 0.61
CCND1 P24385 4/20 0.61
ALDH1A1 P00352 5/20 0.52
TRPA1 O75762 1/20 0.52
ALOX5 P09917 1/20 0.52
MAPK1 P28482 1/20 0.52
CCNB2 O95067 2/20 0.48
CDK1 P06493 2/20 0.48
CCNB1 P14635 2/20 0.48
CCNB3 Q8WWL7 2/20 0.48
TRIM24 O15164 2/20 0.46
TRIM33 Q9UPN9 2/20 0.46
TSHR P16473 1/20 0.46
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL11527287 0.98 LMNA (0.62) LMNAKMT2AMEN1THRBBLM
SCHEMBL11070320 0.92 CDK4 (0.70) LMNAKMT2AMEN1THRBBLM
SCHEMBL16476616 0.92 CDK4 (0.70) LMNAKMT2AMEN1THRBBLM
Ortho-Phthalaldehyde SCHEMBL29412642 0.81 LMNA (1.00) LMNAKMT2AMEN1THRBBLM
Ortho-Phthalaldehyde SCHEMBL4953869 0.81 LMNA (1.00) LMNAKMT2AMEN1THRBBLM
Ortho-Phthalaldehyde SCHEMBL33393 0.81 LMNA (1.00) LMNAKMT2AMEN1THRBBLM
SCHEMBL30518886 0.79 TRPA1 (0.71) LMNACDK4CCND1ALDH1A1TRPA1
SCHEMBL9072393 0.79 CDK4 (0.50) LMNAKMT2AMEN1THRBBLM
Ortho-Phthalaldehyde SCHEMBL6688449 0.78 LMNA (0.93) LMNAKMT2AMEN1THRBBLM
Ortho-Phthalaldehyde SCHEMBL10792496 0.78 LMNA (0.93) LMNAKMT2AMEN1THRBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 287 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12478091-B2 Vaporizable alkaloid compositions and methods of use thereof Ready Mix Naturals, LLC (US) 2025-11-25 US claimed
US-11946083-B2 Method for the microbial production of specific natural capsaicinoids CONAGEN INC. (US) 2024-04-02 US claimed
EP-3765081-B1 ANTIMICROBIAL PHOTOSENSITIZER COMPOSITION TOEFX INC (CA) 2023-11-22 EP claimed
US-20230012268-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF INFLAMMATION WITH STEROIDS AND A MODULATOR BUZZELET DEVELOPMENT AND TECHNOLOGIES LTD (IL) 2023-01-12 US claimed
US-20220403427-A1 METHOD FOR THE MICROBIAL PRODUCTION OF SPECIFIC NATURAL CAPSAICINOIDS CONAGEN INC. (US) 2022-12-22 US claimed
EP-4072558-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF INFLAMMATION WITH STEROIDS AND A MODULATOR Buzzelet Development And Technologies Ltd (IL) 2022-10-19 EP claimed
US-20220233463-A1 LOCAL ANESTHETIC COMPRISING A TRP CHANNEL MODULATOR BUZZELET DEVELOPMENT AND TECHNOLOGIES LTD (IL) 2022-07-28 US claimed
EP-4017486-A1 COMPOSITONS FOR THE TREATMENT OF A CONDITION CHARACTERIZED BY ANANDAMIDE DEFICIENCY AND USES THEREOF Buzzelet Development And Technologies Ltd (IL) 2022-06-29 EP claimed
US-20220168246-A1 COMPOSITONS FOR THE TREATMENT OF A CONDITION CHARACTERIZED BY ANANDAMIDE DEFICIENCY AND USES THEREOF BUZZELET DEVELOPMENT AND TECHNOLOGIES LTD (IL) 2022-06-02 US claimed
EP-3968970-A1 LOCAL ANESTHETIC COMPRISING A TRP CHANNEL MODULATOR Buzzelet Development And Technologies Ltd (IL) 2022-03-23 EP claimed
EP-1635689-A2 METHOD AND KIT FOR CONTROLLING BLEEDING University of Tennessee Research Foundation (US) 2006-03-22 EP claimed
EP-1605956-A1 ADMINISTRATION OF CAPSAICINOIDS Algorx Pharmaceuticals, Inc. (US) 2005-12-21 EP claimed
US-20050020690-A1 Infiltration of capsaicin into surgical sites and open wounds ALGORX (US) 2005-01-27 US claimed
US-20050019436-A1 Injectable capsaicin ALGORX (US) 2005-01-27 US claimed
WO-2004093664-A2 METHOD AND KIT FOR CONTROLLING BLEEDING UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2004-11-04 WO claimed
US-20040202735-A1 Method and kit for controlling bleeding UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2004-10-14 US claimed
WO-2004058286-A1 ADMINISTRATION OF CAPSAICINOIDS ALGORX PHARMACEUTICALS, INC. (US) 2004-07-15 WO claimed
EP-1135490-A1 HUMAN VANILLOID RECEPTORS AND THEIR USES GLAXO GROUP LIMITED (GB) 2001-09-26 EP claimed
WO-2000032766-A1 HUMAN VANILLOID RECEPTORS AND THEIR USES GLAXO GROUP LIMITED (GB) 2000-06-08 WO claimed
US-5759358-A ACRYLIC ACID IN THE PRESENCE OF ALDEHYDES, AMINES AND DISTILLATION ROHM AND HAAS COMPANY (US) 1998-06-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220403427-A1 METHOD FOR THE MICROBIAL PRODUCTION OF SPECIFIC NATURAL CAPSAICINOIDS TRPV1, CYP51A1, NAAA LMNA 4430/4885KMT2A 3039/4885MEN1 4196/4885
US-11946083-B2 Method for the microbial production of specific natural capsaicinoids TRPV1, CYP51A1, NAAA LMNA 4430/4885KMT2A 3039/4885MEN1 4196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.