Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31520127 | 1.00 | MDM4 (0.56) | MDM4TP53HDAC3MAPK1HDAC1 | |
| SCHEMBL6241585 | 0.89 | TIMP3 (0.56) | MDM4TP53HDAC3MAPK1HDAC1 | |
| SCHEMBL15922175 | 0.87 | CA1 (0.57) | MDM4TP53HDAC3MAPK1HDAC1 | |
| SCHEMBL6962126 | 0.86 | MDM4 (0.56) | MDM4TP53HDAC3MAPK1HDAC1 | |
| SCHEMBL1339026 | 0.85 | NPC1 (0.62) | MDM4TP53HDAC3MAPK1HDAC1 | |
| SCHEMBL31520132 | 0.84 | CA1 (0.55) | HDAC3MAPK1HDAC1HDAC2HPGD | |
| SCHEMBL3210059 | 0.84 | NPC1 (0.49) | MDM4TP53HDAC3MAPK1HDAC1 | |
| SCHEMBL6226263 | 0.84 | CA1 (0.75) | MDM4TP53HDAC3MAPK1HDAC1 | |
| SCHEMBL12669228 | 0.83 | CA1 (0.50) | MDM4TP53HDAC3MAPK1HDAC1 | |
| SCHEMBL11831116 | 0.83 | SMN1; SMN2 (0.57) | HDAC3MAPK1HDAC1HDAC2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3784039-A1 | RHEOLOGICAL MODIFIERS FOR SPRAY DRIFT CONTROL IN AGROCHEMICAL EMULSIONS | Rohm and Haas Company (US) | 2021-03-03 | — | — | EP | disclosed |
| US-8110329-B2 | Charge controlling agent and toner | CANON KABUSHIKI KAISHA (JP) | 2012-02-07 | — | — | US | disclosed |
| US-8110329-B2 | Charge controlling agent and toner | CANON KABUSHIKI KAISHA (JP) | 2012-02-07 | — | — | US | disclosed |
| US-20100286149-A1 | NOVEL BENZAMIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2010-11-11 | — | — | US | disclosed |
| EP-2212303-A1 | NOVEL BENZAMIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | NeuroSearch AS (DK) | 2010-08-04 | — | — | EP | disclosed |
| WO-2009068509-A1 | NOVEL BENZAMIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2009-06-04 | — | — | WO | disclosed |
| US-20070111125-A1 | CHARGE CONTROLLING AGENT AND TONER | CANON KABUSHIKI KAISHA (JP) | 2007-05-17 | — | — | US | disclosed |
| US-20070111125-A1 | CHARGE CONTROLLING AGENT AND TONER | CANON KABUSHIKI KAISHA (JP) | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070111125-A1 | CHARGE CONTROLLING AGENT AND TONER | CA2, ACTR2, CA12 | MDM4 3602/4885TP53 3999/4885HDAC3 1039/4885 |
| US-20100286149-A1 | NOVEL BENZAMIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | KCNA2, KCNJ2, KCNB2 | MDM4 4605/4885TP53 4638/4885HDAC3 266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.