Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 9/20 | 0.47 |
| ▸ | CA1 | P00915 | 6/20 | 0.47 |
| ▸ | CA7 | P43166 | 4/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA4 | P22748 | 3/20 | 0.47 |
| ▸ | CA6 | P23280 | 3/20 | 0.47 |
| ▸ | CA5A | P35218 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.47 |
| ▸ | PTGES2 | Q9H7Z7 | 7/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1805343 | 0.79 | CA2 (0.50) | CA2CA1CA7CA14CA12 | |
| SCHEMBL28873594 | 0.78 | CA2 (0.53) | CA2CA1CA7CA14CA12 | |
| SCHEMBL28691043 | 0.77 | CA2 (0.48) | CA2CA1CA7CA14CA12 | |
| SCHEMBL30851195 | 0.75 | ALDH1A1 (0.42) | CA2CA1EPHX2 | |
| SCHEMBL8572706 | 0.75 | ALDH1A1 (0.42) | CA2CA1EPHX2 | |
| SCHEMBL939720 | 0.75 | PTGES2 (0.55) | CA2CA1CA7CA14CA12 | |
| SCHEMBL1807165 | 0.75 | PDIA6 (0.51) | CA2CA1CA7CA14CA12 | |
| SCHEMBL1807384 | 0.75 | PKM (0.58) | CA2CA1CA7CA14CA12 | |
| SCHEMBL395420 | 0.74 | CA2 (0.43) | CA2CA1CA7CA14CA12 | |
| SCHEMBL22606257 | 0.74 | APEX1 (0.47) | CA2CA1CA7CA14CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114072390-A | RAD51 inhibitors | 赛泰尔治疗公司 | 2022-02-18 | — | — | CN | disclosed |