SCHEMBL2893368

SCHEMBL2893368

CCCCC(N=C=N)N(C)C

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL265110 0.98
Hydrochloric Acid SCHEMBL560373 0.76
Hydrochloric Acid SCHEMBL8073418 0.75 CYP1A2 (0.36)
SCHEMBL13847959 0.71
SCHEMBL27764084 0.71 DNM1 (0.33) DNM1
SCHEMBL9812477 0.70 DNM1 (0.37) DNM1
Hydrochloric Acid SCHEMBL28310945 0.66
SCHEMBL2045857 0.65 LMNA (0.38) DNM1
SCHEMBL4692042 0.63 TSHR (0.32)
SCHEMBL9812486 0.62 LMNA (0.35) DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1883721-A Method for modifying artificial implanter by covalent cross-linking gel HARBIN INST OF TECHNOLOGY (CN) 2006-12-27 CN claimed
CN-114423460-A Tough gel-based drug delivery compositions and methods thereof 哈佛学院院长等 2022-04-29 CN disclosed
WO-2020032366-A1 IMMUNOREACTANT CARRIER 주식회사 레모넥스 2020-02-13 WO disclosed
WO-2020027641-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING ATOPIC DISEASES 주식회사 레모넥스 2020-02-06 WO disclosed
WO-2020027585-A2 POLYPEPTIDE DELIVERY COMPOSITION 주식회사 레모넥스 2020-02-06 WO disclosed
WO-2020027640-A1 COMPOSITION FOR INHIBITING CTGF EXPRESSION 주식회사 레모넥스 2020-02-06 WO disclosed
WO-2020027571-A1 PHARMACEUTICAL COMPOSITION FOR WOUND HEALING 주식회사 레모넥스 2020-02-06 WO disclosed
WO-2019022521-A9 COMPOSITION FOR DELIVERING PHYSIOLOGICALLY ACTIVE INGREDIENTS INTO BLOOD VESSEL 주식회사 레모넥스 2019-08-15 WO disclosed
US-20170166543-A1 COMPOSITIONS AND METHODS FOR SYNTHESIZING (2S,3S)-TRANS-EPOXYSUCCINYL-L-LEUCYL-AMIDO-3-METHYLBUTANE ETHYL ESTER AMERICAN LIFE SCIENCE PHARMACEUTICALS INC (US) 2017-06-15 US disclosed
US-9212192-B2 Bicyclic carboxamide inhibitors of kinases ABBVIE INC. (US) 2015-12-15 US disclosed
EP-1347971-A1 THIAZOLYL INHIBITORS OF TEC FAMILY TYROSINE KINASES Bristol-Myers Squibb Company (US) 2003-10-01 EP disclosed
US-6599558-B1 Covalently bonding vinylalkoxysilane and graft polymerizing with further monomers forming hydrophilic layer; inhibiting restenosis and thrombosis POLYBIOMED LIMITED (GB) 2003-07-29 US disclosed
US-20030069238-A1 Thiazolyl inhibitors of Tec family tyrosine kinases BRISTOL-MYERS SQUIBB COMPANY 2003-04-10 US disclosed
EP-0988071-B1 TREATING METAL SURFACES TO ENHANCE BIO-COMPATIBILITY AND/OR PHYSICAL CHARACTERISTICS POLYBIOMED LTD (GB) 2003-02-26 EP disclosed
WO-2002098441-A2 METHOD OF TREATING METABOLIC DISORDERS USING NEURONATIN POLYPEPTIDES AZIGN BIOSCIENCE A/S (DK) 2002-12-12 WO disclosed
WO-2002050071-A1 THIAZOLYL INHIBITORS OF TEC FAMILY TYROSINE KINASES BRISTOL-MYERS SQUIBB COMPANY (US) 2002-06-27 WO disclosed
EP-0988071-A2 TREATING METAL SURFACES TO ENHANCE BIO-COMPATIBILITY AND/OR PHYSICAL CHARACTERISTICS PolyBioMed Limited (GB) 2000-03-29 EP disclosed
WO-1998055162-A2 TREATING METAL SURFACES TO ENHANCE BIO-COMPATIBILITY POLYBIOMED LIMITED (GB) 1998-12-10 WO disclosed
US-5356433-A Using an amino containing organosilane compound CORDIS CORPORATION (US) 1994-10-18 US disclosed
CN-1068110-A dicarboxylic acid derivatives and preparation method thereof TANABE SEIYAKU CO LTD JP (JP) 1993-01-20 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170166543-A1 COMPOSITIONS AND METHODS FOR SYNTHESIZING (2S,3S)-TRANS-EPOXYSUCCINYL-L-LEUCYL-AMIDO-3-METHYLBUTANE ETHYL ESTER PTMS, LTA, LPXN DNM1 4604/4885
US-20030069238-A1 Thiazolyl inhibitors of Tec family tyrosine kinases TEC, LCK, LTK DNM1 3389/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.