Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 15/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22324022 | 0.86 | HCRTR1 (0.36) | HCRTR1HCRTR2 | |
| Trifluoromethanesulfonic Acid SCHEMBL11061442 | 0.78 | KCNH2 (0.40) | — | |
| Trifluoromethanesulfonic Acid SCHEMBL11309126 | 0.75 | DRD2 (0.38) | ACHE | |
| Trifluoromethanesulfonic Acid SCHEMBL10438998 | 0.75 | HSP90AA1 (0.41) | HCRTR2ACHE | |
| Trifluoromethanesulfonic Acid SCHEMBL11064735 | 0.74 | SLC22A12 (0.41) | PTGS2PTGS1ACHESLC22A12 | |
| Trifluoromethanesulfonic Acid SCHEMBL28689987 | 0.73 | ALPL (0.40) | PTGS2PTGS1SLC22A12 | |
| Trifluoromethanesulfonic Acid SCHEMBL11060685 | 0.71 | PPARG (0.41) | PTGS2PTGS1 | |
| Trifluoromethanesulfonic Acid SCHEMBL11060624 | 0.70 | ALDH1A1 (0.39) | PTGS2ACHE | |
| Trifluoromethanesulfonic Acid SCHEMBL11064584 | 0.68 | ALDH1A1 (0.42) | PTGS2PTGS1SLC22A12 | |
| Trifluoromethanesulfonic Acid SCHEMBL11064376 | 0.68 | KCNH2 (0.36) | PTGS2PTGS1SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114126613-A | Methods and compositions for modulating splicing | 斯基霍克疗法公司 | 2022-03-01 | — | — | CN | disclosed |