Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | TNK2 | Q07912 | 3/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2893456 | 1.00 | PDE4B (0.39) | PDE4BHRH3GPR119TNK2MCHR1 | |
| SCHEMBL2893458 | 0.85 | PDE4B (0.37) | PDE4BHRH3TNK2MCHR1KCNH2 | |
| SCHEMBL2893972 | 0.78 | PTGS2 (0.40) | MCHR1MEN1KMT2A | |
| SCHEMBL2893969 | 0.78 | PTGS2 (0.40) | MCHR1MEN1KMT2A | |
| SCHEMBL2887433 | 0.77 | MEN1 (0.38) | PDE4BHRH3GPR119TNK2MCHR1 | |
| SCHEMBL2890476 | 0.74 | MCHR1 (0.55) | HRH3MCHR1KCNH2 | |
| SCHEMBL2890481 | 0.74 | MCHR1 (0.55) | HRH3MCHR1KCNH2 | |
| SCHEMBL15224181 | 0.70 | ESR1 (0.54) | MEN1KMT2A | |
| SCHEMBL15869163 | 0.70 | TNK2 (0.35) | TNK2MEN1KMT2AHSD11B1 | |
| SCHEMBL15869172 | 0.70 | TNK2 (0.35) | TNK2MEN1KMT2AHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732456-B2 | Pyridone derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-06-08 | — | — | US | disclosed |
| US-20070208046-A1 | Pyridone derivative | MSD K.K. (JP) | 2007-09-06 | — | — | US | disclosed |
| EP-1741703-A1 | PYRIDONE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-01-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208046-A1 | Pyridone derivative | CHRM1, XDH, MTR | PDE4B 2767/4885HRH3 28/4885GPR119 2063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.