Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 4/20 | 0.55 |
| ▸ | MMP13 | P45452 | 4/20 | 0.55 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28705417 | 1.00 | MMP9 (0.55) | MMP9MMP13ADAM17MMP1HDAC8 | |
| SCHEMBL28935319 | 1.00 | MMP9 (0.55) | MMP9MMP13ADAM17MMP1HDAC8 | |
| SCHEMBL28694225 | 1.00 | MMP9 (0.55) | MMP9MMP13ADAM17MMP1HDAC8 | |
| SCHEMBL6340106 | 0.93 | CA1 (0.53) | MMP9MMP13ADAM17MMP1HDAC8 | |
| SCHEMBL2489271 | 0.82 | MMP1 (0.40) | MMP9MMP13ADAM17MMP1CA1 | |
| SCHEMBL11486933 | 0.81 | GNAI3 (0.41) | MMP9MMP13ADAM17MMP1TP53 | |
| SCHEMBL19712174 | 0.81 | TP53 (0.48) | CA2TP53GPR84FFAR1 | |
| SCHEMBL2486962 | 0.80 | TP53 (0.42) | MMP9MMP13ADAM17MMP1TP53 | |
| SCHEMBL7609463 | 0.79 | GPR84 (0.53) | CA2TP53GPR84FFAR1HDAC1 | |
| SCHEMBL3495263 | 0.79 | GPR84 (0.53) | CA2TP53GPR84FFAR1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057614-B | Hydroxamic acid sulfonic acid compound, and preparation method and application thereof | 广东省科学院资源利用与稀土开发研究所 | 2023-05-23 | — | — | CN | disclosed |
| CN-114057614-A | Hydroximic acid sulfonic acid compound and preparation method and application thereof | 广东省科学院资源利用与稀土开发研究所 | 2022-02-18 | — | — | CN | disclosed |