Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | FLT4 | P35916 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | PI4KA | P42356 | 1/20 | 0.47 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.47 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 9-Benzyl-6-Methoxy-9H-Purine SCHEMBL28939425 | 0.85 | HPGD (0.77) | HPGDDAPK1LMNAMEN1HTT | |
| SCHEMBL28963715 | 0.78 | GAA (0.42) | HPGDLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL3395811 | 0.77 | HSP90AA1 (0.57) | HPGDDAPK1LMNARECQLMEN1 | |
| SCHEMBL29424867 | 0.75 | HPGD (0.56) | HPGDDAPK1RECQLMEN1HTT | |
| SCHEMBL22533420 | 0.75 | HPGD (0.56) | HPGDDAPK1RECQLMEN1HTT | |
| SCHEMBL5458724 | 0.74 | YTHDC1 (0.61) | HPGDDAPK1ADORA2AADORA1 | |
| SCHEMBL17364335 | 0.73 | ADORA2A (0.60) | HPGDDAPK1RECQLMEN1HTT | |
| SCHEMBL17115735 | 0.72 | DAPK1 (1.00) | HPGDDAPK1HTTADORA2API4KA | |
| SCHEMBL15214193 | 0.71 | SLC29A1 (0.46) | HPGDLMNAMEN1HTTKMT2A | |
| SCHEMBL22326733 | 0.71 | ADORA2A (0.62) | HPGDDAPK1LMNAFLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114524815-B | 8-alkoxypurine derivative and preparation method and application thereof | 华南理工大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-114524815-A | 8-alkoxy purine derivative and preparation method and application thereof | 华南理工大学 | 2022-05-24 | — | — | CN | disclosed |