Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.77 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.75 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.63 |
| ▸ | PI4KA | P42356 | 1/20 | 0.63 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.63 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.63 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.63 |
| ▸ | FLT4 | P35916 | 1/20 | 0.63 |
| ▸ | KDR | P35968 | 1/20 | 0.63 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.57 |
| ▸ | PDE4A | P27815 | 1/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.55 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17115735 | 0.86 | DAPK1 (1.00) | HPGDDAPK1ADORA2API4KAPI4K2B | |
| SCHEMBL28939424 | 0.85 | HPGD (0.59) | HPGDDAPK1ADORA2API4KAPI4K2B | |
| SCHEMBL22533420 | 0.83 | HPGD (0.56) | HPGDDAPK1ADORA2API4KAPI4K2B | |
| SCHEMBL29424867 | 0.83 | HPGD (0.56) | HPGDDAPK1ADORA2API4KAPI4K2B | |
| SCHEMBL30983894 | 0.82 | DAPK1 (0.65) | HPGDDAPK1ADORA2API4KAPI4K2B | |
| SCHEMBL30983811 | 0.80 | DAPK1 (0.62) | HPGDDAPK1ADORA2API4KAPI4K2B | |
| SCHEMBL3395811 | 0.80 | HSP90AA1 (0.57) | HPGDDAPK1FLT4KDRHTT | |
| SCHEMBL2980291 | 0.79 | ADORA2A (0.70) | HPGDDAPK1ADORA2API4KAPI4K2B | |
| SCHEMBL30984022 | 0.79 | ADORA2A (0.70) | HPGDDAPK1ADORA2API4KAPI4K2B | |
| SCHEMBL17364335 | 0.79 | ADORA2A (0.60) | HPGDDAPK1ADORA2API4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114524815-B | 8-alkoxypurine derivative and preparation method and application thereof | 华南理工大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-114524815-A | 8-alkoxy purine derivative and preparation method and application thereof | 华南理工大学 | 2022-05-24 | — | — | CN | disclosed |