Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.35 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12179242 | 0.79 | CNR1 (0.42) | SMN1; SMN2RAB9ANPC1CNR1BAZ2B | |
| SCHEMBL459529 | 0.77 | P4HTM (0.42) | P4HTMSMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL22227949 | 0.77 | P4HTM (0.55) | P4HTMSMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL24756311 | 0.76 | ALDH1A1 (0.54) | SMN1; SMN2RAB9AALDH1A1GAAMAPT | |
| SCHEMBL28940905 | 0.76 | P4HTM (0.36) | P4HTMSMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL28941020 | 0.76 | HDAC1 (0.37) | P4HTMSMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL28940972 | 0.75 | CNR1 (0.43) | P4HTMRAB9ANPC1CNR1ALDH1A1 | |
| SCHEMBL28940920 | 0.75 | ACR (0.40) | P4HTMSMN1; SMN2ALDH1A1KDM4EKMT2A | |
| SCHEMBL28940979 | 0.75 | CNR2 (0.38) | P4HTMSMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL25738793 | 0.74 | PLK1 (0.50) | SMN1; SMN2RAB9ANPC1BAZ2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | claimed |
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |