Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 4/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21379396 | 0.85 | P4HTM (0.36) | PDE10AP4HTMNPC1ALDH1A1GAA | |
| SCHEMBL22341998 | 0.82 | P4HTM (0.48) | CNR2NAMPTP4HTMNPC1ALDH1A1 | |
| SCHEMBL28941122 | 0.78 | MAPK8 (0.38) | P4HTM | |
| SCHEMBL28940972 | 0.76 | CNR1 (0.43) | P4HTMNPC1ALDH1A1GAARAB9A | |
| SCHEMBL28940920 | 0.76 | ACR (0.40) | NAMPTP4HTMGABRA5ALDH1A1SMN1; SMN2 | |
| SCHEMBL22341853 | 0.75 | ANO1 (0.50) | — | |
| SCHEMBL28940976 | 0.75 | P4HTM (0.41) | P4HTMNPC1ALDH1A1GAARAB9A | |
| SCHEMBL28940875 | 0.74 | P4HTM (0.38) | P4HTMNPC1ALDH1A1GAARAB9A | |
| SCHEMBL28940978 | 0.74 | SCN9A (0.39) | CNR2NAMPTPDE10AGABRA5CFTR | |
| SCHEMBL17298873 | 0.73 | NPC1 (0.52) | CNR2NPC1ALDH1A1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | claimed |
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |