Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19145297 | 0.82 | CNR1 (0.51) | CNR1MMP13OPRM1OPRL1MEN1 | |
| SCHEMBL21379406 | 0.81 | NAMPT (0.48) | CNR1P4HTMGCGRMAOB | |
| SCHEMBL21379396 | 0.80 | P4HTM (0.36) | CNR1KDM4EALDH1A1POLBP4HTM | |
| SCHEMBL15228258 | 0.77 | KDM4E (0.42) | CNR1OPRM1OPRL1MEN1KMT2A | |
| SCHEMBL28940920 | 0.76 | ACR (0.40) | MEN1KMT2AKDM4EALDH1A1P4HTM | |
| SCHEMBL28940979 | 0.76 | CNR2 (0.38) | ALDH1A1P4HTMNPC1RAB9AGAA | |
| SCHEMBL28940976 | 0.75 | P4HTM (0.41) | CNR1KMT2AKDM4EALDH1A1P4HTM | |
| SCHEMBL19105518 | 0.73 | RAB9A (0.47) | CNR1MMP13OPRM1OPRL1POLB | |
| SCHEMBL28292622 | 0.73 | ANO1 (0.45) | CNR1KMT2APOLB | |
| SCHEMBL22341930 | 0.73 | P2RX7 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | claimed |
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |