Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27600842 | 0.80 | GAA (0.36) | TDP1MAPK1L3MBTL1TSHRALDH1A1 | |
| SCHEMBL27787098 | 0.67 | NAMPT (0.50) | L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL7060682 | 0.66 | MMP8 (0.56) | TDP1MAPK1L3MBTL1TSHRALDH1A1 | |
| SCHEMBL10962901 | 0.66 | MEN1 (0.50) | TDP1ALDH1A1LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL27522636 | 0.66 | ALDH1A1 (0.48) | TDP1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL27787137 | 0.66 | LDHA (0.50) | TDP1MAPK1L3MBTL1TSHRALDH1A1 | |
| SCHEMBL27374014 | 0.65 | KMT2A (0.48) | TDP1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL10964454 | 0.64 | EPHX2 (0.47) | TDP1MAPK1L3MBTL1TSHRALDH1A1 | |
| SCHEMBL27531556 | 0.64 | KDM4E (0.46) | TDP1MAPK1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL230068 | 0.64 | ALDH1A1 (0.50) | TDP1ALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100357280-C | Dihydronaphthalene devivatives and drugs contanining these compounds as active ingrdeient | ONO PHARMACENTICAL CO LTD (JP) | 2007-12-26 | — | — | CN | disclosed |
| CN-1489582-A | Dihydronaphthalene devivatives and drugs contanining these compounds as active ingrdeient | СҰҩƷ��ҵ��ʽ���� | 2004-04-14 | — | — | CN | disclosed |