Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 6/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14392660 | 0.85 | CCR3 (0.40) | CNR2CCR3TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL14368712 | 0.81 | L3MBTL1 (0.53) | CCR3MEN1KMT2A | |
| SCHEMBL28783271 | 0.81 | L3MBTL1 (0.53) | CCR3MEN1KMT2A | |
| SCHEMBL14368778 | 0.80 | TAS1R3 (0.49) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL27757451 | 0.80 | CCR3 (0.48) | CCR3MEN1KMT2ANPC1RAB9A | |
| SCHEMBL28944630 | 0.80 | TAS1R3 (0.49) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL14368806 | 0.77 | CCR3 (0.50) | CCR3KMT2ANPC1RAB9A | |
| SCHEMBL4429053 | 0.77 | CCR3 (0.50) | CCR3KMT2ANPC1RAB9A | |
| SCHEMBL14368805 | 0.76 | PLK1 (0.44) | CCR3KMT2ANPC1RAB9A | |
| SCHEMBL14368810 | 0.76 | ALDH1A1 (0.53) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101484442-A | Compounds that are agonists of muscarinic receptors and tha may be effective in treating pain, alzheimer's disease and/or schizophrenia | ASTRAZENECA AB (SE) | 2009-07-15 | — | — | CN | claimed |
| CN-101484442-A | Compounds that are agonists of muscarinic receptors and tha may be effective in treating pain, alzheimer's disease and/or schizophrenia | ASTRAZENECA AB (SE) | 2009-07-15 | — | — | CN | disclosed |