Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CHKA | P35790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28059417 | 0.92 | TRPM8 (0.37) | TRPM8ALDH1A1MEN1TP53KMT2A | |
| SCHEMBL21952207 | 0.82 | — | — | |
| SCHEMBL16611870 | 0.80 | — | — | |
| SCHEMBL7292726 | 0.80 | RAB9A (0.36) | TRPM8ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL16361179 | 0.80 | — | — | |
| SCHEMBL12958892 | 0.80 | — | — | |
| SCHEMBL8431500 | 0.80 | — | — | |
| SCHEMBL19817080 | 0.78 | TRPM8 (0.36) | TRPM8ALDH1A1NPC1RAB9A | |
| SCHEMBL17572811 | 0.75 | PKM (0.32) | TRPM8RAB9A | |
| SCHEMBL16661734 | 0.75 | L3MBTL1 (0.38) | TRPM8ALDH1A1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101646650-B | Sub-type selective azabicycloalkane derivatives | TARGACEPT INC | 2012-06-13 | — | — | CN | disclosed |
| CN-101646650-A | Sub-type selective azabicycloalkane derivatives | TARGACEPT INC US | 2010-02-10 | — | — | CN | disclosed |