Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | RGS12 | O14924 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
| ▸ | LCK | P06239 | 1/20 | 0.55 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.55 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.53 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.45 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.45 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.45 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27815829 | 0.84 | EGFR (0.58) | NOX4MAPTEGFRCA1CA2 | |
| SCHEMBL12862660 | 0.81 | ALDH1A1 (0.57) | ALDH1A1NOX4MAPTTDP1RGS12 | |
| SCHEMBL608498 | 0.77 | KDM4C (0.53) | ALDH1A1NOX4MAPTTDP1RGS12 | |
| SCHEMBL608886 | 0.77 | KDM4C (0.50) | ALDH1A1NOX4MAPTTDP1RGS12 | |
| SCHEMBL608754 | 0.77 | NOX4 (0.61) | ALDH1A1NOX4MAPTTDP1RGS12 | |
| SCHEMBL10767712 | 0.77 | KAT8 (0.56) | ALDH1A1NOX4MAPTTDP1RGS12 | |
| SCHEMBL156253 | 0.77 | ALDH1A1 (0.60) | ALDH1A1NOX4MAPTTDP1RGS12 | |
| SCHEMBL17849006 | 0.77 | KDM4C (0.63) | ALDH1A1NOX4MAPTTDP1RGS12 | |
| SCHEMBL4116154 | 0.76 | KDM4C (0.52) | ALDH1A1NOX4MAPTTDP1RGS12 | |
| SCHEMBL21451256 | 0.76 | ALDH1A1 (0.56) | ALDH1A1NOX4MAPTTDP1RGS12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101874016-A | Manufacturing method of 2-hydroxy-5-phenylalkylaminobenzoic acid derivatives and their salts | NEUROTECH CO LTD | 2010-10-27 | — | — | CN | claimed |
| CN-101874016-B | Manufacturing method of 2-hydroxy-5-phenylalkylaminobenzoic acid derivatives and their salts | NEUROTECH CO LTD | 2013-06-19 | — | — | CN | disclosed |
| CN-101874016-A | Manufacturing method of 2-hydroxy-5-phenylalkylaminobenzoic acid derivatives and their salts | NEUROTECH CO LTD | 2010-10-27 | — | — | CN | disclosed |