Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.56 |
| ▸ | RGS12 | O14924 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | LCK | P06239 | 1/20 | 0.56 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.55 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21451252 | 0.87 | BCL2L1 (0.50) | ALDH1A1MAPTNOX4RGS12EGFR | |
| SCHEMBL17849006 | 0.81 | KDM4C (0.63) | ALDH1A1MAPTNOX4RGS12EGFR | |
| SCHEMBL12862660 | 0.79 | ALDH1A1 (0.57) | ALDH1A1MAPTNOX4RGS12EGFR | |
| SCHEMBL156253 | 0.78 | ALDH1A1 (0.60) | ALDH1A1MAPTNOX4RGS12EGFR | |
| SCHEMBL28944697 | 0.76 | ALDH1A1 (0.55) | ALDH1A1MAPTNOX4RGS12EGFR | |
| SCHEMBL4575689 | 0.76 | ALDH1A1 (0.55) | ALDH1A1MAPTNOX4RGS12EGFR | |
| SCHEMBL727904 | 0.75 | KDM4C (0.57) | ALDH1A1MAPTNOX4RGS12EGFR | |
| SCHEMBL15339785 | 0.75 | ALDH1A1 (0.57) | ALDH1A1MAPTNOX4RGS12EGFR | |
| SCHEMBL10767712 | 0.75 | KAT8 (0.56) | ALDH1A1MAPTNOX4RGS12EGFR | |
| SCHEMBL18331069 | 0.75 | CA1 (0.59) | ALDH1A1MAPTNOX4RGS12EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210387941-A1 | Diphenyl-like Compound, Intermediate Thereof, Preparation Method Therefor, Pharmaceutical Composition Thereof And Uses Thereof | SHANGHAI MAXINOVEL PHARMACEUTICALS CO., LTD. (CN) | 2021-12-16 | — | — | US | disclosed |
| US-11078192-B2 | Aromatic acetylene or aromatic ethylene compound, intermediate, preparation method, pharmaceutical composition and use thereof | GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD. | 2021-08-03 | — | — | US | disclosed |
| US-20190308957-A1 | AROMATIC ACETYLENE OR AROMATIC ETHYLENE COMPOUND, INTERMEDIATE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD (CN) | 2019-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210387941-A1 | Diphenyl-like Compound, Intermediate Thereof, Preparation Method Therefor, Pharmaceutical Composition Thereof And Uses Thereof | CD274, PDCD1LG2, PDCD1 | ALDH1A1 48/4885MAPT 1667/4885NOX4 2608/4885 |
| US-20190308957-A1 | AROMATIC ACETYLENE OR AROMATIC ETHYLENE COMPOUND, INTERMEDIATE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | PDCD1, CD274, PDCD1LG2 | ALDH1A1 35/4885MAPT 408/4885NOX4 4553/4885 |
| US-11078192-B2 | Aromatic acetylene or aromatic ethylene compound, intermediate, preparation method, pharmaceutical composition and use thereof | PDCD1, CD274, PDCD1LG2 | ALDH1A1 35/4885MAPT 408/4885NOX4 4553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.