Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | RGS12 | O14924 | 1/20 | 0.60 |
| ▸ | EGFR | P00533 | 1/20 | 0.60 |
| ▸ | LCK | P06239 | 1/20 | 0.60 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.60 |
| ▸ | PPARA | Q07869 | 1/20 | 0.55 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.55 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12862660 | 0.86 | ALDH1A1 (0.57) | KDM4CALDH1A1MAPTNOX4TDP1 | |
| SCHEMBL20999134 | 0.86 | BCL2L1 (0.53) | KDM4CALDH1A1MAPTNOX4TDP1 | |
| SCHEMBL10767712 | 0.82 | KAT8 (0.56) | KDM4CALDH1A1MAPTNOX4TDP1 | |
| SCHEMBL156253 | 0.82 | ALDH1A1 (0.60) | KDM4CALDH1A1MAPTNOX4TDP1 | |
| SCHEMBL21451256 | 0.81 | ALDH1A1 (0.56) | KDM4CALDH1A1MAPTNOX4TDP1 | |
| SCHEMBL10759621 | 0.81 | KAT8 (0.58) | KDM4CALDH1A1MAPTNOX4TDP1 | |
| SCHEMBL4575689 | 0.80 | ALDH1A1 (0.55) | KDM4CALDH1A1MAPTNOX4TDP1 | |
| SCHEMBL727904 | 0.79 | KDM4C (0.57) | KDM4CALDH1A1MAPTNOX4TDP1 | |
| SCHEMBL6225148 | 0.79 | KDM4E (0.46) | KDM4CALDH1A1MAPTNOX4TDP1 | |
| SCHEMBL15339785 | 0.79 | ALDH1A1 (0.57) | KDM4CALDH1A1MAPTNOX4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107001412-B | Compounds of the N-acylamino-amide family, compositions containing them and uses | 莱雅公司 | 2021-03-12 | — | — | CN | disclosed |
| EP-3233886-B1 | COMPOUNDS IN THE FAMILY OF N-ACYLAMINO-AMIDES, COMPOSITIONS COMPRISING THEM, AND USES | OREAL (FR) | 2020-02-26 | — | — | EP | disclosed |
| EP-3483142-A1 | AROMATIC ACETYLENE OR AROMATIC ETHYLENE COMPOUND, INTERMEDIATE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Guangzhou Maxinovel Pharmaceuticals Co., Ltd. (CN) | 2019-05-15 | — | — | EP | disclosed |
| US-10098827-B2 | Compounds in the family of N-acylamino-amides, compositions comprising them, and uses | L'OREAL (FR) | 2018-10-16 | — | — | US | disclosed |
| US-20170360667-A1 | NEW COMPOUNDS IN THE FAMILY OF N-ACYLAMINO-AMIDES, COMPOSITIONS COMPRISING THEM, AND USES | L'OREAL (FR) | 2017-12-21 | — | — | US | disclosed |
| EP-3233886-A1 | COMPOUNDS IN THE FAMILY OF N-ACYLAMINO-AMIDES, COMPOSITIONS COMPRISING THEM, AND USES | L'Oréal (FR) | 2017-10-25 | — | — | EP | disclosed |
| CN-107001412-A | Compound in N acyl aminoacid amides family, include their compositions and purposes | 莱雅公司 | 2017-08-01 | — | — | CN | disclosed |
| WO-2016096804-A1 | COMPOUNDS IN THE FAMILY OF N-ACYLAMINO-AMIDES, COMPOSITIONS COMPRISING THEM, AND USES | L'OREAL (FR) | 2016-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170360667-A1 | NEW COMPOUNDS IN THE FAMILY OF N-ACYLAMINO-AMIDES, COMPOSITIONS COMPRISING THEM, AND USES | H1-0, CRY1, CCNA1 | KDM4C 712/4885ALDH1A1 736/4885MAPT 3886/4885 |
| US-10098827-B2 | Compounds in the family of N-acylamino-amides, compositions comprising them, and uses | CRY1, H1-0, C1R | KDM4C 783/4885ALDH1A1 636/4885MAPT 3591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.