Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GRK6 | P43250 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 7/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15641524 | 0.83 | TTR (0.47) | KEAP1NFE2L2KDM4EALDH1A1MAPT | |
| SCHEMBL6105501 | 0.82 | KDM4E (0.48) | KEAP1NFE2L2KDM4EALDH1A1MAPT | |
| SCHEMBL8517076 | 0.81 | BCAT2 (0.44) | KEAP1NFE2L2KDM4EALDH1A1MAPT | |
| SCHEMBL589633 | 0.77 | HTR6 (0.53) | KDM4EALDH1A1HPGDTSHRF2 | |
| SCHEMBL40536 | 0.77 | ALDH1A1 (0.54) | KEAP1NFE2L2KDM4EALDH1A1MAPT | |
| SCHEMBL7093462 | 0.77 | CA9 (0.37) | KDM4EF2PRSS1PRSS2PRSS3 | |
| SCHEMBL161331 | 0.72 | KDM4E (0.53) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL14776287 | 0.72 | KDM4E (0.41) | KEAP1NFE2L2KDM4EALDH1A1MAPT | |
| SCHEMBL998313 | 0.71 | MMP2 (0.48) | KEAP1NFE2L2KDM4EALDH1A1MAPT | |
| SCHEMBL29991060 | 0.71 | CD44 (0.46) | KEAP1NFE2L2KDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515934-A | NAMPT modulators | 赛特凯恩蒂克公司 | 2022-12-23 | — | — | CN | disclosed |