SCHEMBL28945801

SCHEMBL28945801

O=C(NNS(=O)(=O)CCl)c1coc2ccc(Oc3ccccc3)cc2c1=O

nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOB P27338 18/20 0.51
MAOA P21397 4/20 0.47
ACHE P22303 1/20 0.45
NPC1 O15118 1/20 0.45
POLB P06746 1/20 0.45
RAB9A P51151 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6720384 0.78 MAOB (0.61) MAOBMAOAACHENPC1POLB
SCHEMBL7950720 0.66 MAOB (0.79) MAOBMAOAL3MBTL1
SCHEMBL10614660 0.64 NPC1 (1.00) MAOAACHENPC1POLBRAB9A
SCHEMBL13856154 0.63 KMT2A (0.83) MAOBMAOANPC1RAB9AL3MBTL1
SCHEMBL6720375 0.63 MAOB (0.69) MAOBMAOANPC1RAB9AL3MBTL1
SCHEMBL11362721 0.62 NPC1 (0.62) MAOBMAOANPC1POLBRAB9A
SCHEMBL11356469 0.61 NPC1 (0.61) MAOBNPC1POLBRAB9AL3MBTL1
SCHEMBL13856106 0.61 MAOB (0.61) MAOBMAOANPC1RAB9AL3MBTL1
SCHEMBL27516743 0.61 MAOA (0.57) MAOBMAOAL3MBTL1
SCHEMBL2813471 0.61 NPC1 (0.48) MAOBMAOANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115667212-A High-purity N- (5-methoxy-2-phenoxyphenyl) methanesulfonamide and process for producing the same 富士胶片富山化学株式会社 2023-01-31 CN disclosed