Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 12/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29933548 | 0.89 | ALDH1A1 (0.77) | MAOBALDH1A1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL3375297 | 0.89 | ALDH1A1 (0.77) | MAOBALDH1A1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL11508405 | 0.88 | ALDH1A1 (0.60) | MAOBALDH1A1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL11362721 | 0.87 | NPC1 (0.62) | MAOBALDH1A1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL11260734 | 0.87 | MAOB (0.64) | MAOBALDH1A1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6720393 | 0.86 | MAOB (0.54) | MAOBALDH1A1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL13856154 | 0.85 | KMT2A (0.83) | MAOBALDH1A1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL12325869 | 0.85 | NPC1 (0.74) | MAOBALDH1A1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL11260728 | 0.84 | ALDH1A1 (0.65) | MAOBALDH1A1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6720384 | 0.83 | MAOB (0.61) | MAOBALDH1A1RAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023070780-A1 | MONOAMINE OXIDASE B INHIBITOR HAVING POTENTIAL IRON CHELATING ACTIVITY AND USE THEREOF | 浙江工业大学 | 2023-05-04 | — | — | WO | disclosed |
| CN-114149417-A | Monoamine oxidase B inhibitor with potential iron chelation activity and application thereof | 浙江工业大学 | 2022-03-08 | — | — | CN | disclosed |
| US-8183236-B2 | Compounds with HIV-1 integrase inhibitory activity and use thereof as anti-HIV/AIDS therapeutics | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2012-05-22 | — | — | US | disclosed |
| US-8183236-B2 | Compounds with HIV-1 integrase inhibitory activity and use thereof as anti-HIV/AIDS therapeutics | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2012-05-22 | — | — | US | disclosed |
| US-20090088420-A1 | COMPOUNDS WITH HIV-1 INTEGRASE INHIBITORY ACTIVITY AND USE THEREOF AS ANTI-HIV/AIDS THERAPEUTICS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2009-04-02 | — | — | US | disclosed |
| US-20090088420-A1 | COMPOUNDS WITH HIV-1 INTEGRASE INHIBITORY ACTIVITY AND USE THEREOF AS ANTI-HIV/AIDS THERAPEUTICS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090088420-A1 | COMPOUNDS WITH HIV-1 INTEGRASE INHIBITORY ACTIVITY AND USE THEREOF AS ANTI-HIV/AIDS THERAPEUTICS | TYMP, IMPDH1, SAMHD1 | MAOB 1441/4885ALDH1A1 265/4885RAB9A 3114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.