Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 13/20 | 0.79 |
| ▸ | MAOA | P21397 | 7/20 | 0.79 |
| ▸ | PTGES | O14684 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956495 | 0.88 | MAOB (0.79) | MAOBMAOAL3MBTL1PKMCASP3 | |
| SCHEMBL15211605 | 0.85 | MAOB (0.58) | MAOBMAOACASP3SENP8SENP7 | |
| SCHEMBL7950756 | 0.82 | MAOB (0.64) | MAOBMAOA | |
| SCHEMBL27516742 | 0.82 | MAOB (0.58) | MAOBMAOAPTGESPTGS2L3MBTL1 | |
| SCHEMBL24471022 | 0.82 | MAOB (0.66) | MAOBMAOAL3MBTL1PKMCASP3 | |
| SCHEMBL30569409 | 0.81 | MAOB (0.60) | MAOBMAOAL3MBTL1PKMCASP3 | |
| SCHEMBL24470811 | 0.81 | MAOB (0.60) | MAOBMAOAL3MBTL1PKMCASP3 | |
| SCHEMBL27516743 | 0.79 | MAOA (0.57) | MAOBMAOAL3MBTL1PKMCASP3 | |
| SCHEMBL26103188 | 0.79 | MAOB (0.65) | MAOBMAOACASP3SENP8SENP7 | |
| SCHEMBL20258227 | 0.77 | ALDH1A1 (0.65) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218427-B1 | AS ENDOTHELIN RECEPTOR ANTAGONIST | SHIONOGI & CO., LTD. (JP) | 2001-04-17 | — | — | US | disclosed |
| EP-0924207-A1 | CHROMENE-3-CARBOXYLATE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1999-06-23 | — | — | EP | disclosed |